Novel Treatment of Allergic Fungal Sinusitis Using Omalizumab

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Novel treatment of allergic fungal sinusitis using omalizumab

A case report of recalcitrant allergic fungal sinusitis (AFS) refractory to systemic corticosteroids and multiple functional endoscopic sinus surgeries (FESSs) treated with anti-IgE antibody omalizumab is reported. AFS is often classified with chronic rhinosinusitis (CRS). Although similar symptoms are among the two diseases, AFS has a unique pathophysiology. Patients with AFS demonstrate type ...

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Allergic Fungal Sinusitis in Children

Allergic fungal sinusitis (AFS) is a benign, extramucosal, noninvasive fungal sinus disease representing an allergic/hypersensitivity response to extramucosal fungal pathogens in the sinus [1]. It occurs mainly in immunocompetent patients, in contrast to invasive fungal diseases that usually involve an immunocompromised host. The incidence of AFS in patients affected by chronic rhinosinusitis a...

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Allergic Fungal Sinusitis: CT Findings1

1 From the Departments of Radiology (5KM., J.G.A., M.C.), Surgery (S.K.M.), Pathology (L.L.C.), and Otolaryngology (K.R.J.), University of North Carolina School of Medicine, 3324 Old Infirmary CB 751 0, Chapel Hill, NC 27599-751 0; the Departments of Radiology(R.EF)andOtolaryngology(S.B.K.), Medical College of Georgia, Augusta; the Department of Radiology, M.D. Anderson Cancer Center, Houston, ...

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BACKGROUND Allergic fungal sinusitis (AFS) is a form of fungal disease that has recently been considered a distinct clinicopathologic entity. Other forms of fungal sinusitis include acute-fulminant (invasive), chronic indolent (invasive) and mycetoma (non-invasive). Objectives were to assess the presentation and to describe the diagnostic techniques for allergic fungal sinusitis in our setup. ...

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ژورنال

عنوان ژورنال: Allergy & Rhinology

سال: 2014

ISSN: 2152-6567,2152-6567

DOI: 10.2500/ar.2014.5.0098